Search results for "Anti-acetylcholine receptor antibodies"

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Comparative analysis of biochip mosaic-based indirect immunofluorescence with enzyme-linked immunosorbent assay for diagnosing myasthenia gravis

2021

Background: The detection of anti-acetylcholine receptor (AChR) and anti-muscle-specific tyrosine kinase (MuSK) antibodies is useful in myasthenia gravis (MG) diagnosis and management. BIOCHIP mosaic-based indirect immunofluorescence is a novel analytical method, which employs the simultaneous detection of anti-AChR and anti-MuSK antibodies in a single miniature incubation field. In this study, we compare, for the first time, the BIOCHIP MG mosaic with conventional enzyme-linked immunosorbent assay (ELISA) in the diagnosis of MG. Methods: A total of 71 patients with MG diagnosis were included in the study. Anti-AChR and anti-MuSK antibodies were measured separately by two different ELISA an…

Medicine (General)ConcordanceClinical BiochemistryAnti-muscle-specific tyrosine kinase antibodiesArticleR5-920DiagnosisMedicineBiochipMyasthenia gravischemistry.chemical_classificationIndirect immunofluorescencebiologybusiness.industryBiomarkermedicine.diseaseMolecular biologyMyasthenia gravismyasthenia gravis; diagnosis; biomarker; anti-acetylcholine receptor antibodies; anti-muscle-specific tyrosine kinase antibodies; BIOCHIPEnzymechemistrybiology.proteinAntibodybusinessBIOCHIPKappaAnti-acetylcholine receptor antibodies

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